We’ve been going through an extended difficult season with Paul’s overall health. I appreciate firm reminders that God’s wisdom is guiding things to the best possible eternal result.
From Wayne Grudem’s Making Sense of Who God Is: One of Seven Parts from Grudem’s Systematic Theology, p. 83.
God’s wisdom means that God always chooses the best goals and the best means to those goals. This definition goes beyond the idea of God knowing all things and specifies that God’s decisions about what he will do are always wise decisions: that is, they always will bring about the best results (from God’s ultimate perspective), and they will bring about those results through the best possible means.
Scripture affirms God’s wisdom in general in several places. He is called “the only wise God” (Rom. 16:27). Job says that God “is wise in heart” (Job 9:4), and “With him are wisdom and might; he has counsel and understanding” (Job 12:13). God’s wisdom is seen specifically in creation. The psalmist exclaims, “O Lord, how manifold are your works! In wisdom you have made them all; the earth is full of your creatures” (Ps. 104:24).
And some of those ‘all’ will be made by God to live with disabilities (Exodus 4:11). I’m grateful that God always chooses the best goals AND the best means. He is entirely worthy to be worshiped for his wisdom.
The Works of God 
My mind easily and often wanders to a man-centered perspective of struggles and challenges – thank you for this reminder.